Category: Speaker Interviews

Lessons from the Worm: Novel Insights for the Nrf2 Cytoprotection Pathways

Dr. Curran’s lab is interested in understanding the molecules, genes and cells that impact aging and age-related diseases. They utilize a multidisciplinary approach that combines genetics, functional genomics, biochemistry, cell and molecular biology, and physiology to comprehensively study the complexities of the universal process of aging.

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Hungry Neurons: An Interview With Dr. Zachary Knight on How We Respond to Food.

Dr. Knight’s lab studies neural circuits in the mouse that control feeding and other motivated behaviors central to survival. The labs goal is to understand how these circuits are able to sense the needs of the body and then generate the specific behavioral responses that restore homeostasis. During the seminar, Dr. Knight described how the brain’s “hunger circuit” governs eating.

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Interview with Dr. Rae Matsumoto: How Addiction Causes Neorodegeration

One can see these specific pattern changes repeatedly in aging, Parkinson’s, Alzheimer’s and methamphetamine related neurodegeneration. These mechanisms are only part of the cause of neurodegeneration. I think of methamphetamine as another contributing factor by which cellular function could become compromised, leading to neurodegeneration.

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Creating and Working at the World Renown San Francisco Exploratorium

Have you ever visited a science or discovery museum and thought “how do they make this happen?” or “how amazing it must be to create an exhibit!” Dr. Kristina Yu, the Director of the Living Systems Department at San Francisco’s Exploratorium, answered both of these questions during a recent visit with the scientists at the Buck Institute.

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Interview with Dr. Blake Rasmussen: The Role of mTORC1 Signaling in Human Sarcopenia

I think the way we eat should be addressed. For instance, most individuals consume all of their daily protein at one, maybe two meals during the day. The problem is that only so much of that protein gets used, the rest then gets stored as fat. Usually the high protein meals are lunch and dinner, and dinner is often the meal with the least physical activity following it…we need a 30-30-30 plan.

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Interview with Dr. Pankaj Kapahi: How Diet Influences Aging and Age Related Diseases

One of the big picture ideas is questioning the universality of the aging process. Does aging occur the same way in diabetics, cancer patients and normal individuals? At the same time we are also trying to focus on a particular age-related diseases like diabetic complications, while also trying to achieve a deeper understanding in the invertebrate models and examine their relevance in mammalian models.

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